Cancer type | Cell line | FL118 EC50 (95%CI) (nM) | SN-38 EC50 (95% CI) (nM) | RP | RR(FL118) | RR(SN-38) |
---|---|---|---|---|---|---|
NSCLC | H460 | 0.31 (0.21-0.47) | 2.84 (1.98-4.09) | 9.2 | Â | Â |
 | EKVX | 0.56 (0.38-0.83) | 2.58 (1.73-3.80) | 4.6 |  |  |
 | A549 | 0.86 (0.61-1.22) | 4.17 (2.30-7.57) | 4.8 |  |  |
Colorectal cancer | SW620 | 0.30 (0.19-0.46) | 1.82 (1.06-3.10) | 6.1 | Â | Â |
 | HCT8 | 0.28 (0.15-0.53) | 2.21 (1.38-3.55) | 7.9 |  |  |
 | HCT116 | 0.36 (0.27-0.48) | 3.15 (2.42-4.10) | 8.8 |  |  |
 |  HCT116-SN6 | 2.28 (1.70-3.05) | 7.63 (6.14-9.48) | 3.3 | 6.3 | 2.4 |
 |  HCT116-G7 | 4.14 (2.78-6.16) | 20.3 (13.9-29.6) | 4.9 | 11.5 | 6.4 |
 |  HCT116-SN50 | 4.04 (2.79-5.86) | 135 (80.4-226) | 33.4 | 11.2 | 42.9 |
 |  HCT116-A2 | 2.13 (1.48-3.07) | 51.5(37.4-70.8) | 24.2 | 5.9 | 16.3 |