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Figure 3 | Molecular Cancer

Figure 3

From: Long noncoding RNA, CCDC26, controls myeloid leukemia cell growth through regulation of KIT expression

Figure 3

Silencing of the CCDC26 locus in KD clones. A: A map of chromosomal region 8q24 in the vicinity of CCDC26 (128,800,000–130,800,000; sequence numbering is according to the human genome assembly, GRCh37/hg19). Exon-intron structures are not shown. Arrows indicate the direction of transcription. Location and gene annotation are summarized in the table below. B: Expression of CCDC26-short, CCDC26-long, LOC728724, GSDMC, THS1, THS2, human AK015428 homolog (hAK015428), PVTC1 and MYC. Graphs are shown in the log2 scale. C: Treatment with trichostatin A (TSA) and 5-aza-2′-deoxycytidine (AzdC) prevented the suppression of GSDMC but not CCDC26. Open and filled boxes indicate with or without TSA + AzdC, respectively.

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