Skip to main content
Figure 4 | Molecular Cancer

Figure 4

From: Quercetin inhibits HGF/c-Met signaling and HGF-stimulated melanoma cell migration and invasion

Figure 4

Quercetin suppressed the activation of c-Met downstream molecules. (A, B and C) A375 and A2058 cells were treated with indicated concentrations of quercetin for 24 h. (D) A2058 cells were starved overnight and then exposed to the vehicle or quercetin (60 μM) for 6 h. After that, these cells were stimulated with or without HGF (100 ng/ml) for 10 min. For each experiment, the whole-cell lysates were prepared and probed by Western blot using specific antibodies. Independent experiments were performed at least three times, and the results from a representative experiment are shown. The relative expression levels were analyzed by Image J software and shown as mean ± S.D., *P < 0.05, **P < 0.01.

Back to article page