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Table 3 Expression of selected genes affected by ectopic HOTAIR overexpression according to Gupta et al. [15], Kim et al. [18] and Li et al. [21] in comparison with microarray data from transfected bladder cancer cell lines

From: The long noncoding RNA HOTAIR has tissue and cell type-dependent effects on HOX gene expression and phenotype of urothelial cancer cells

 

Gupta et al. mamma

Kim et al. pancreas

Kim et al. pancreas

Li et al. esophagus

Heubach et al. bladder

Heubach et al. bladder

 

MDA-MB-231

MiaPaCa2

Panc28

KYSE180

VM-CUB1

5637

JAM2

down

down

up

down

--

--

PCDH10

down

down

up

down

--

--

PCDHB5

down

down

up

down

down

--

ABL2

up

down

up

n.c.

up

down

SNAIL1

up

up

up (n.s.)

down

down

down

LAMB3

up

down

n.c.

down

down

--

LAMC2

up

down

down (n.s.)

n.c.

down

down

GDF15

--

down

n.s.

up

up

up

IL29

--

down

up

n.c.

--

--

IL28A

--

down

n.s.

n.c.

--

--

IL28B

--

down

up

n.c.

--

--

IFTM1

--

up

n.s.

--

--

--

OAS1

--

up

n.s.

up

--

up

MX1

--

down

n.s.

up

down

up

  1. Abbreviations: n.s. not significant, −- not detected.