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Table 1 Sphere-forming frequency, diameter and/or self-renewal ability of cells from colonospheres of stably transfected with pCMV (Vector), pCMV/miR-145 (miR-145) colon cancer HCT-116 cells

From: miR-21 and miR-145 cooperation in regulation of colon cancer stem cells

  Vector miR-145 P value
Sphere-forming frequency (95% CI) 1/11 (1/17-1/4) 1/88 (1/196-1/40) <0.001
Diameter (μm) 104.0 ± 18.5 47.0 ± 13.2 <0.001
Self-renewal (spheres per 200 cells) 13 ± 3 - <0.001
  1. Data are pooled from three independent experiments for each. CI, confidence interval.