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Table 1 Sphere-forming frequency, diameter and/or self-renewal ability of cells from colonospheres of stably transfected with pCMV (Vector), pCMV/miR-145 (miR-145) colon cancer HCT-116 cells

From: miR-21 and miR-145 cooperation in regulation of colon cancer stem cells

 

Vector

miR-145

P value

Sphere-forming frequency (95% CI)

1/11 (1/17-1/4)

1/88 (1/196-1/40)

<0.001

Diameter (μm)

104.0 ± 18.5

47.0 ± 13.2

<0.001

Self-renewal (spheres per 200 cells)

13 ± 3

-

<0.001

  1. Data are pooled from three independent experiments for each. CI, confidence interval.
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Molecular Cancer

ISSN: 1476-4598