Skip to main content
Figure 8 | Molecular Cancer

Figure 8

From: Na/K-ATPase as a target for anticancer drugs: studies with perillyl alcohol

Figure 8

POH-induced apoptosis in U87 cells. U87 in the control condition (Control, A). The cells were treated with 0.5 mM POH (POH, B) and 0.5 mM POH plus 0.5 μM JNK inhibitor V (POH + IJNK, C). After 24 hours, the cells were immunostained for cleaved caspase-3 and the number of positive cells was analyzed (D). Whereas POH induced cell apoptosis, the addition of the JNK inhibitor completely inhibited this effect. The addition of DMSO or JNK inhibitor V alone had no effect on cell death. Scale bar: 20 μm.*P < 0.050, analyzed by Student’s t-test.

Back to article page