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Fig. 1 | Molecular Cancer

Fig. 1

From: Targeting the insulin-like growth factor receptor and Src signaling network for the treatment of non-small cell lung cancer

Fig. 1

Co-activation of IGF-1R and Src in NSCLCs. (a) A comparison of mRNA levels of IGF-1R and Src in a dataset of lung cancer tissue specimens retrieved from cBioPortal (http://www.cbioportal.org/public-portal/). OR: odds ratio. (b) Correlation between pIGF-1R and pSrc in a tissue microarray. Rs: Spearman’s correlation coefficient. The significance of the correlation between pIGF-1R/IR and pSrc membrane levels was assessed using the Spearman Rank correlation test. (c) Protein and mRNA expression was examined via Western blot and RT-PCR analyses, respectively

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