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Fig. 3 | Molecular Cancer

Fig. 3

From: Genomic analysis and selective small molecule inhibition identifies BCL-XL as a critical survival factor in a subset of colorectal cancer

Fig. 3

Colon cancer cell lines with high BCL-XL and NOXA are more sensitive to BCL-XL inhibitor. a Protein expression of BCL-2 family members in colorectal cancer cell lines. BCL2L1 copy number gains >3 is indicated with + or -. b Protein and mRNA expression of BCL-XL, NOXA, MCL-1, and ratio of BCL-XL /MCL-1 in A-1155463-sensitive vs. resistant colorectal cancer cell lines

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