Fig. 6
From: Bergapten drives autophagy through the up-regulation of PTEN expression in breast cancer cells
Bergapten treatment reduces cell viability in MCF-7 and ZR-75 cells. MTT assay in MCF-7 and ZR-75 cells treated for 16 h (panel a, b), 24 h (panel c, d), 48 h (panel e, f) with vehicle (−), Bg 20 μM, Bg 50 μM, or pre-treated for 4 h respectively with 5 mM 3-MA (3-Methiladenine) or 10 μM ZVF (Z-VAD-fmk) as indicated. Columns are mean of three independent experiments and expressed as % over vehicle, which was assumed to be 100 %; bars, SD; *P < 0.05 vs vehicle. ** P < 0.05 vs Bg 50 μM