Table 2 Top 10 differentially expressed piRNA clusters (A), tRNA-derived small RNAs (B) and miRNAs (C)

A

Genomic location

Log2 Fold Change

P-value (adjusted)

1

chr15:21,925,462-21,930,432

−6.18

2.62e-29

2

chr15:20,841,664-20,850,393

−6.18

1.31e-27

3

chr15:23,510,099-23,514,854

−6.25

1.46e-26

4

chr18:55,837,529-55,838,674

inf

1.46e-26

5

chr1:2,237,998-2,241,778

−6.55

1.88e-26

6

chr15:23,386,898-23,404,357

−6.06

1.88e-26

7

chr15:28,583,287-28,593,483

−5.93

1.88e-26

8

chr4:190,801,280-190,804,618

−6.21

1.88e-26

9

chr15:20,723,798-20,737,584

−5.94

3.27e-26

10

chr18:14,460,205-14,464,963

−6.30

3.27e-26

B

tRNA

Log2 Fold Change

P-value (adjusted)

1

Glu-GAG (chr13, 45492060)

−2.51

2.50e-09

2

Glu-GAG (chr15, 26327380)

−2.63

2.50e-09

3

Asp-GAY (chrX, 18996334)

−3.49

3.40e-06

C

miRNA

Log2 Fold Change

p-value (adjusted)

1

hsa-miR-302d-3p

11.25

1.95e-13

2

hsa-miR-302a-3p

11.65

1.23e-12

3

hsa-mir-302b

11.38

1.23e-12

4

hsa-mir-302a

11.18

7.26e-12

5

hsa-miR-367-3p

10.20

1.48e-11

6

hsa-miR-371a-5p

9.29

2.09e-11

7

hsa-miR-371b-3p

9.29

2.09e-11

8

hsa-miR-302c-5p

Inf

3.45e-11

9

hsa-miR-302d-5p

Inf

1.38e-10

10

hsa-miR-302c-3p

11.32

1.38e-10