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Fig. 4 | Molecular Cancer

Fig. 4

From: The pseudokinase SgK223 promotes invasion of pancreatic ductal epithelial cells through JAK1/Stat3 signaling

Fig. 4

Enhanced Stat3 activation in SgK223-overexpressing cells is not mediated via Src. a Overexpression of SgK223 in HPDE cells increases Csk expression and decreases Src activity. Data are normalized and expressed as in the previous figures. *indicates significance with a P-value < 0.05, ***indicates significance with a P-value < 0.0005. b The Src inhibitor Saracatinib does not affect Stat3 expression or activation

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