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Fig. 6 | Molecular Cancer

Fig. 6

From: The pseudokinase SgK223 promotes invasion of pancreatic ductal epithelial cells through JAK1/Stat3 signaling

Fig. 6

SgK223 signals via JAK1/Stat3. a Overexpression of SgK223 enhances JAK1 activation. Data are normalized and expressed as in Fig. 3. *indicates significance with a P-value < 0.05. b-c Activation of Stat3 in SgK223-overexpressing cells is JAK-dependent. b AG490 or c CP690550 were applied for 2 h prior to cell lysis. Cell lysates were then Western blotted as indicated

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Molecular Cancer

ISSN: 1476-4598