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Table 1 Tumorigenicity of A549-shSFN in SCID mice

From: Stratifin accelerates progression of lung adenocarcinoma at an early stage

 

shRNA

T (%)

D (%)

DM (%)

Intrabronchial

shSFN#1

0/4 (0)

0/4 (0)

0/4 (0)

(n = 4)

shSFN#2

2/4 (50)

0/4 (0)

0/4 (0)

 

shLuc

4/4 (100)

1/4 (25)

0/4 (0)

Intravenous

shSFN#1

0/4 (0)

0/4 (0)

0/4 (0)

(n = 4)

shSFN#2

0/4 (0)

0/4 (0)

0/4 (0)

 

shLuc

4/4 (100)

3/4 (75)

0/4 (0)

  1. T tumor development, D intrathoracic dissemination by gross appearance, DM distant metastasis. Liver and brain were analyzed as examples of common sites of lung cancer metastasis