Fig. 3

Reduced GYLTL1B and ISPD expression independently predict increase mortality for clear cell carcinoma patients. Analysis of overall mortality risk, adjusted for sex and age. a. Separate analyses for each gene. b. A joint analysis of the entire pathway. In both a and b, a ten-fold downregulation of the indicated genes corresponds to the given increase in risk of death (right of the axis). 95 % confidence intervals are shown by the horizontal bar. P values are listed to the right of the respective genes. c. Kaplan-Meier survival curve generated from patients with downregulation of the stated gene greater than 1 standard deviation from the mean. d. Table showing number studied, deaths, and median survival values for Kaplan-Meier curve