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Fig. 5 | Molecular Cancer

Fig. 5

From: Serine/arginine-rich splicing factor 3 (SRSF3) regulates homologous recombination-mediated DNA repair

Fig. 5

Knockdown of SRSF3 increases accumulation of DSBs and impairs HRR activity. a Western blotting result of γ-H2AX. Cell lysates were prepared from cell cultures treated with or without Doxy for 3 days. b Immunofluorescent staining of γ-H2AX in A2780/SRSF3si2 cells treated with or without Doxy for 3 days. c Results of HRR assays. Shown are the percentage of GFP-positive cells determined by flow cytometry (mean ± s.d., n = 4)

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Molecular Cancer

ISSN: 1476-4598