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Fig. 1 | Molecular Cancer

Fig. 1

From: MicroRNA-1908 functions as a glioblastoma oncogene by suppressing PTEN tumor suppressor pathway

Fig. 1

miR-1908 is upregulated in glioblastoma cells, GSCs, and human tumors and inversely correlates with patient survival. a Quantification of miR-1908 in glioblastoma cell lines (A127, SW1783, U87, U373, LN-229, SW1088, HS683, HFU251, SNB19 and T98G)) and stem cell lines (GSCs; 802 and 1228) showing higher expression than in normal human astrocytes. b Average expression of miR-1908 in glioblastoma cells, GSGs and normal human astrocytes. c Quantification of miR-1908 in human glioblastoma tumors (T) and normal human brain (N). d Quantification of miR-1908 in normal brain, stageI-IIglioblastoma and stage III-IV glioblastoma, (e) Correlation analysis of expression data and patient survival data from Affiliated Hospital of Guilin Medical University showing that miR-1908 levels are a risk indicator for survival. **p < 0.01 and ##p < 0.01 based on the Student t test. ##: Student t test between stage I-IIglioblastoma and stage III-IV glioblastoma. Error bars, SD

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