Fig. 7
From: MicroRNA-1908 functions as a glioblastoma oncogene by suppressing PTEN tumor suppressor pathway
miR-1908 activates both AKT/FOXO3a and AKT/mTOR signaling pathway. a and b Western blot analysis of phospho-P13K, total P13K (T-AKT), phospho-AKT, total AKT (T-AKT), phospho-S6K1, total S6K1, phospho-4E-BP1, and total 4E-BP1 in indicated cells. c, d, e and f Protein expression and relative mRNA quantitation of p21 and cyclin D1 in indicated cells. g ICH for phosphor-P13K, phospho-AKT, phospho-S6K1 and phospho-4E-BP1 in miR-1908 overexpressing tumors. **P < 0.01 based on the Student t test. Error bars, SD