Fig. 3
From: Retinoic acid-induced CHD5 upregulation and neuronal differentiation of neuroblastoma
TrkA and CHD5 expression in NB cell lines. NB cell lines were treated with 5 or 10 μM of 13cRA for 3, or 12 days as indicated. CHD5 and TrkA was upregulated in (a) SY5Y, (b) NGP and (c) SK-N-DZ cell lines whereas (d) IMR5, (e) LAN5, and (f) SK-N-FI cells did not show a significant change in either CHD5 or TrkA gene expression upon with 13cRA treatment. Values were normalized (GAPDH) and calculated as relative levels of CHD5 and TrkA expression in untreated samples. The graphs show the results of at least three independent experiments in triplicates (SD). Statistical analysis was performed using one-way ANOVA using Prism followed by Tukey’s post-test and P-values were reported as shown. ns = not significant