Fig. 1
The level of FXR is positively correlated with that of miR-122. a and b The expression of FXR mRNA (a) and mature miR-122 (b) in 20 human HCC tissues and the corresponding adjacent noncancerous tissues was detected by qRT-PCR. c The correlation between the levels of FXR and miR-122 in HCC tissues was analyzed using Pearson’s test (R 2 = 0.61, P < 0.01). d The expression of FXR mRNA and mature miR-122 in HCC cell lines (HepG2, Hep3B, Huh7, PLC, SMMC-7721, MHCC97L and MHCC97H) and hepatic cell line L02 was assayed by qRT-PCR. e The correlation between the levels of FXR and miR-122 in HCC cell lines was analyzed using Pearson’s test (R 2 = 0.95, P < 0.01). β-actin was used as a control for FXR examination, while U6 snRNA as a control for miR-122 detection