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Fig. 4 | Molecular Cancer

Fig. 4

From: Carbon ion beam combined with cisplatin effectively disrupts triple negative breast cancer stem-like cells in vitro

Fig. 4

a. Clustergram of Custom RT-PCR Array of CSCs delivered from MDA-MB-231 cells 5 days after a carbon ion beam, X-ray alone or in combination with 25 μM of cisplatin (CDDP). CDDP was added prior to irradiation and treated for 5 days. b. Expression of apoptosis- and autophagy-related genes after carbon ion beam, X-ray alone or in combination with CDDP in CSCs. c. Expression CSC markers after carbon ion beam, X-ray alone or in combination with CDDP in CSCs. d. Expression of angiogenesis-, metastasis-related genes after carbon ion beam, X-ray alone or in combination with CDDP in CSCs. e. Expression of DNA repair-related genes after carbon ion beam, X-ray alone or in combination with CDDP in CSCs. f. Expression of cell cycle-related genes after carbon ion beam, X-ray alone or in combination with CDDP in CSCs. *, p < 0.01, compared to control. All experiments were performed in triplicate (n = 3)

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Molecular Cancer

ISSN: 1476-4598