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Fig. 3 | Molecular Cancer

Fig. 3

From: Long non-coding RNA TUG1 is up-regulated in hepatocellular carcinoma and promotes cell growth and apoptosis by epigenetically silencing of KLF2

Fig. 3

Effects of down-regulation of TUG1 on tumor growth in vivo. a Tumors from mice 16 days after injection of HepG2 cells stably transfected with sh-TUG1 or empty vector. b The tumor volume was calculated every four days after injection of HepG2 cells stably transfected with sh-TUG1 or empty vector. Points, mean (n = 5); bars indicate S.D. c Tumor weights are represented as means of tumor weights ± s.d. d QPCR analysis of TUG1 expression in tumor tissues formed from HepG2/sh-TUG1, HepG2/empty vector. e Tumors developed from sh-TUG1 transfected HepG2 cells showed lower Ki-67 protein levels than tumors developed by control cells. Left: H & E staining; Right: immunostaining. *P < 0.05, **P < 0.01

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