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Fig. 5 | Molecular Cancer

Fig. 5

From: Long non-coding RNA TUG1 is up-regulated in hepatocellular carcinoma and promotes cell growth and apoptosis by epigenetically silencing of KLF2

Fig. 5

Over-expression of KLF2 expression inhibit HepG2 cells proliferation and improve apoptosis. a The mRNA level of KLF2 in HepG2 and Hep3B cells transfected with pCMV-Tag2B-KLF2 was detected by qPCR. b,c MTT assays and colony-forming assays were used to determine the cell viability for pCMV-Tag2B-KLF2 -transfected HepG2 and Hep3B cells. Values represent the mean ± s.d. from three independent experiments. d Apoptosis was determined by flow cytometry. UL, necrotic cells; UR, terminal apoptotic cells; LR, early apoptotic cells. *P < 0.05 and **P < 0.01

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Molecular Cancer

ISSN: 1476-4598