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Fig. 5 | Molecular Cancer

Fig. 5

From: Aldolase B inhibits metastasis through Ten–Eleven Translocation 1 and serves as a prognostic biomarker in hepatocellular carcinoma

Fig. 5

ALDOB inhibits cell migration partly though the elevation of TET1. a Differentially expressed genes in SMMC7721-ALDOB cells compared with control cells. The top 10 up/down-regulated genes are listed on the right. b Relative expression of TET1 in ALDOB stably expressing cells and paired controls. The expression of TET1 was analyzed by RT-PCR and western blot and was normalized to β-actin. c Relative expression of TET1 in HepG2 and Huh7 cells with siALDOB and in paired controls. The expression of TET1 was analyzed by RT-PCR and western blot and was normalized to β-actin. d Transwell migration assays showed that siTET1 could partly relieve the inhibitory effect induced by ALDOB. Scale bars, 200 μM. The statistical analysis is shown in (e)

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Molecular Cancer

ISSN: 1476-4598