Fig. 2
From: Phosphoproteomic analysis reveals Smarcb1 dependent EGFR signaling in Malignant Rhabdoid tumor cells
GO annotation enrichment analysis of differentially phosphorylated proteins. a Gene ontology (GO) annotations enrichment among proteins found to be differentially phosphorylated between SMARCB1 proficient and deficient cells. Evaluated using the David Bioinformatics tool, x-axis indicates log base for Benjamini corrected P-value. Violet dataset represents differentially phosphorylated peptides in high serum; green dataset represents differentially phosphorylated peptides in serum starvation. b Scatter plots depicting Smarcb1 dependent differentially phosphorylated peptides and their expression level in high or low serum. Negative values denote highly expressed/phosphorylated in Smarcb1 deficient cells, positive values denote highly expressed/phosphorylated in Smarcb1 proficient cells. Peptides corresponding to enriched GO categories (from panel 2a) are highlighted in red. Group 1 includes GO annotations: Cytoskeleton, Actin cytoskeleton and focal adhesion. Group 2: Cell cycle. Group 3: Small GTPase regulator activity, protein kinase activity and protein tyrosine kinase activity