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Table 1 Kinases for which phosphorylated target sites were found enriched in Smarcb1 deficient cells. The table depicts kinases, their target residues and relative abundances of the phosphorylated peptide in SMARCB1 proficient/deficient cells (given as the log2 ratio). Kinase targets were defined as described in Materials and methods section. Enrichment for targets was assessed using the GSEA algorithm [53, 54]. Calculated Normalized Enrichment score for kinase targets (KS test): ERK2 = 1.85; ERK1 = 1.66; AKT1 = 1.36; JNK1 = 1.41. Calculated false discovery rate: ERK2 = 0.01; ERK1 = 0.032; AKT1 = 0.223; JNK1 = 0.205

From: Phosphoproteomic analysis reveals Smarcb1 dependent EGFR signaling in Malignant Rhabdoid tumor cells

Kinase Target Residue Log2 (SMARCB1/pMIG)
  Cdc25b S351 −1.12
  Tsc2 S939 −1.65
AKT1 Gsk3b S9 −1.69
  Bad S155 −2.21
  Rps6 S236 −2.28
  Acly S455 −2.31
  Rell1 T262 −1.20
  Dcp1a S335 −1.23
  Dcp1a S339 −1.23
  Junb S256 −1.35
  Mybbp1a S1280 −1.36
  Ugdh T474 −1.38
  Supv3l1 S725 −1.52
ERK2 Rps6ka1 S369 −1.78
  Dennd4c S1270 −2.04
  Ndel1 T219 −2.06
  Atf2 T53 −2.08
  Tpx2 T369 −2.39
  Jun S246 −2.87
  Ahnak S2985 −3.08
  Ahnak S4879 −3.39
  Egfr T695 −3.99
  Pxn S83 −1.18
  Junb S256 −1.35
  Rps6ka1 S369 −1.78
ERK1 Ndel1 T219 −2.06
  Ranbp3 S58 −2.07
  Atf2 T53 −2.08
  Jun S73 −2.76
  Jun S63 −3.69
  Atf2 T51 −2.08
JNK1 Atf2 T53 −2.08
  Jun S73 −2.76
  Jun S63 −3.69