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Fig. 1 | Molecular Cancer

Fig. 1

From: Downregulation of ASPP2 in pancreatic cancer cells contributes to increased resistance to gemcitabine through autophagy activation

Fig. 1

Downregulation of ASPP2 in Pancreatic cancer tissues. a mRNA from pancreatic cancer tissues and para-cancerous tissues was extracted and RT–qPCR analysis was performed to determine the expression of ASPP2; b Pancreatic cancer tissues and para-cancerous tissues from 12 patients were collected and Western Blot assay was performed to analyze the ASPP2 expression; c 65 Pancreatic cancer tissues and para-cancerous tissues were analyzed by immunohistochemical method to determine ASPP2 expression level. Representative samples were shown. The bar graph shows the statistical analysis of ASPP2 in pancreatic cancer tissues and para-cancerous tissues. d The disease-free and overall survival rates of patients of c were compared between the low-ASPP2 and high-ASPP2 groups. Data represent the mean ± SD of three independent experiments (*P < 0.05, **P < 0.01)

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Molecular Cancer

ISSN: 1476-4598