Skip to main content

Table 1 Correlation between LC3/ALDH1 coexpression and clinicopathological profiles

From: Blockade of autophagy reduces pancreatic cancer stem cell activity and potentiates the tumoricidal effect of gemcitabine

Characteristic

Low LC3/ALDH1

High LC3/ALDH1

P

Age, median (range)

67 (38–85)

64 (37–85)

 

Sex

   

  Male

37 (68.5)

23 (59.0)

0.342

  Female

17 (31.5)

16 (41.0)

 

Tumor location

   

  Head

28 (51.9)

29 (74.4)

0.177

  Neck

5 (9.3)

2 (5.1)

 

  Body/tail

12 (22.2)

4 (10.3)

 

  Uncinate process

9 (16.7)

4 (10.3)

 

Tumor size

   

   < 3 cm

30 (55.6)

22 (56.4)

0.935

   ≥ 3 cm

24 (44.4)

17 (43.6)

 

Lymph nodes

   

  Negative

30 (55.6)

16 (41.0)

0.167

  Positive

24 (44.4)

23 (59.0)

 

Margin status

   

  R0

41 (75.9)

25 (64.1)

0.462

  R1

11 (20.4)

12 (30.8)

 

  R2

2 (3.7)

2 (5.1)

 

Tumor grade

   

  Poorly diff.

11 (20.4)

6 (15.4)

0.345

  Moderate diff.

25 (46.3)

24 (61.5)

 

  Well diff.

18 (33.3)

9 (23.1)

 

Stage

   

  I

10 (18.5)

1 (2.6)

0.097

  II

40 (74.1)

36 (92.3)

 

  III

3 (5.6)

1 (2.6)

 

  IV

1 (1.9)

1 (2.6)

 

CA19-9

   

   < 37U/ml

12 (22.2)

8 (20.5)

0.843

   ≥ 37U/ml

42 (77.8)

31 (79.5)

 

Adjuvant therapy

   

  Yes

26 (48.1)

11 (28.2)

0.053

  No

28 (51.9)

28 (71.8)

 

Diabetes mellitus

   

  Yes

18 (33.3)

11 (28.2)

0.598

  No

36 (66.7)

28 (71.8)

 

Survival

   

  Yes

35 (64.8)

12 (30.8)

0.001

  No

19 (35.2)

27 (69.2)

 

Recurrence

   

  Yes

26 (48.1)

35 (89.7)

0.000

  No

28 (51.9)

4 (10.3)

 
  1. The bold value indicates P < 0.05