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Table 2 Outcomes of assessable patients with pancreatic cancer according to protein expression

From: Blockade of autophagy reduces pancreatic cancer stem cell activity and potentiates the tumoricidal effect of gemcitabine

Variable Overall survival Disease-free survival
  HR 95 % CI P HR 95 % CI P
LC3
  Low (n = 50) 1 0.087–0.589 0.200 1 0.251–1.387 0.226
  High (n = 43) 0.227    0.590   
ALDH1
  Low (n = 51) 1 0.516–3.684 0.522 1 0.315–1.481 0.335
  High (n = 42) 1.378    0.684   
LC3/ALDH1
  Low (n = 54) 1 1.622–13.739 0.004 1 2.535–17.170 0.000
  High (n = 39) 4.721    6.597   
OPN
  Low (n = 58) 1 0.233–2.430 0.634 1 0.442–4.234 0.587
  High (n = 35) 0.752    1.368   
OPN/LC3/ALDH1
  Low (n = 42) 1 Reference   1 Reference  
  Moderate (n = 28) 1.770 0.846–3.704 0.130 1.351 0.773–2.362 0.291
  High (n = 23) 2.385 1.129–5.038 0.023 2.245 1.183–4.259 0.013
OPN/CD44/CD133
  Low (n = 39) 1 Reference   1 Reference  
  Moderate (n = 42) 1.929 0.897–4.146 0.093 1.639 0.889–3.021 0.113
  High (n = 12) 4.527 1.403–14.604 0.011 4.140 1.672–10.254 0.002
  1. The bold value indicates P < 0.05