Fig. 1
From: Alcohol-dysregulated miR-30a and miR-934 in head and neck squamous cell carcinoma
RNA-sequencing analysis identifies 8 microRNAs that are associated with alcohol consumption. (a) Kaplan-Meier analysis indicates that increased alcohol consumption leads to poorer patient survival in our patient population (n = 42). (b) Venn diagram schematic conveying our approach to determine the 8 alcohol-associated miRNAs. Each circle represents a comparison of the drinkers versus non-drinkers in each of the categories (smokers, non-smokers, or inclusion of all patients). (c) Heatmaps represent the reads per million miRNA mapped (RPKM) of the most statistically significant dysregulated miRNAs between drinkers and non-drinkers. miRNAs are listed by order of p-value with the most significant located towards the top. (d) Log-transformed miR-30a and (e) miR-934 expression levels in drinkers versus non-drinkers. The middle bar represents the mean, the top and bottom borders represent the 25th and 75th percentile, and the whiskers reach the 5th and 95th percentile. The circles represent outliers