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Fig. 5 | Molecular Cancer

Fig. 5

From: Alcohol-dysregulated miR-30a and miR-934 in head and neck squamous cell carcinoma

Fig. 5

miR-30a and miR-934 knockdown in HNSCC cell lines results in the upregulation of predicted tumor suppressor target genes. (a) Putative sequences targeted by miR-30a within the 3’ UTR of BNIP3L, PRDM1, and SEPT7. (b) The three predicted targets are significantly upregulated in the UMSCC-10B and UMSCC-22B cell lines following inhibition of miR-30a (48 h). (c) Putative sequences targeted by miR-934 within the 3’ UTR of HOXA4, HIPK2, and MLL3. (d) The three predicted targets exhibit increased expression in UMSCC-10B and UMSCC-22B 48 h after knockdown of miR-934. All data is presented as the mean and error bars represent standard deviation. *p<0.05, **p<0.01, ***p<0.001, Student’s t-test

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