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Fig. 1 | Molecular Cancer

Fig. 1

From: Nuclear-enriched abundant transcript 1 as a diagnostic and prognostic biomarker in colorectal cancer

Fig. 1

Whole blood NEAT1 expression in screening and validation phase. a, Plots representing different expression of NEAT1_v1 between normal controls (NC, n=30) and colorectal cancer (CRC, n=30) patients. b, Plots representing different expression of NEAT1_v2. c, Whole blood NEAT1_v1 yielded an AUC value of 0.732 (95 % CI: 0.602-0.838), with 56.7 % sensitivity and 86.7 % specificity in distinguishing colorectal cancer patients from NCs. d, Whole blood NEAT1_v2 yielded an AUC value of 0.845 (95% CI: 0.728-0.925), with 83.3 % sensitivity and 83.3 % specificity in distinguishing colorectal cancer patients from NCs. e, Plots representing different expression of NEAT1_v1 between another groups of NC (n=100) and CRC patients (n=100). f, Plots representing different expression of NEAT1_v2. G, ROC curve of NEAT1_v1 from another groups yielded an AUC value of 0.787 (95 % CI: 0.724-0.842), with 69.0 % sensitivity and 79.0 % specificity in distinguishing colorectal cancer patients from NCs. h, ROC curve of NEAT1_v2 from another groups yielded an AUC value of 0.871 (95 % CI: 0.816-0.914), with 70.0 % sensitivity and 96.0 % specificity in distinguishing colorectal cancer patients from NCs. i, Plots illustrating different levels of NEAT1_v1 versus TNM staging. j, Plots illustrating different levels of NEAT1_v2 versus TNM staging. *P<0.05, **P<0.001, ***P<0.0001

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