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Table 1 Relationship between NEAT1 and clinical features of patients with colon cancer in the whole blood

From: Nuclear-enriched abundant transcript 1 as a diagnostic and prognostic biomarker in colorectal cancer

Clinical variables

Classification

N

NEAT1_v1

NEAT1_v2

Mean

P value

Mean

P value

Gender

Male

101

6.26

0.098

1.65

0.987

 

Female

90

5.38

 

1.65

 

Age (years)a

<56

100

5.60

0.253

1.62

0.769

 

≥56

91

6.21

 

1.69

 

Tumor (T) stage

T1–2

26

6.16

0.287

1.46

0.476

 

T3–4

165

5.80

 

1.68

 

Nodal (N) status

N0

95

5.45

0.287

1.54

0.464

 

N1

48

6.02

 

1.65

 
 

N2

48

6.45

 

1.87

 

Distant metastasis (M)

M0

170

5.52

0.023*

1.63

0.532

 

M1

21

8.49

 

1.84

 

AJCC stageb

I–II

94

5.45

0.144

1.55

0.374

 

III–IV

97

6.23

 

1.74

 

Lymphovascular invasion

No

141

5.55

0.497

1.70

0.463

 

Yes

50

6.67

 

1.52

 

Perineural invasion

No

163

5.55

0.549

1.67

0.701

 

Yes

28

7.54

 

1.55

 

Extranodal tumor deposits

No

163

5.53

0.139

1.66

0.800

 

Yes

28

7.66

 

1.58

 

Differentiation

G1–G2

149

5.92

0.587

1.64

0.880

 

G3–G4

42

5.57

 

1.68

 

Pathology

Adenocarcinoma

164

5.93

0.412

1.68

0.465

 

Mucinous or signet-ring carcinoma

27

5.30

 

1.46

 

Maximum size (cm)a

<5

118

6.02

0.344

1.67

0.687

 

>5

73

5.48

 

1.58

 
  1. *A two-tailed p value ≤0.05 was considered statistically significant
  2. aThe mean age and tumor size, respectively
  3. bAbbreviations: AJCC, American Joint Committee on Cancer (AJCC)