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Table 1 Relationship between NEAT1 and clinical features of patients with colon cancer in the whole blood

From: Nuclear-enriched abundant transcript 1 as a diagnostic and prognostic biomarker in colorectal cancer

Clinical variables Classification N NEAT1_v1 NEAT1_v2
Mean P value Mean P value
Gender Male 101 6.26 0.098 1.65 0.987
  Female 90 5.38   1.65  
Age (years)a <56 100 5.60 0.253 1.62 0.769
  ≥56 91 6.21   1.69  
Tumor (T) stage T1–2 26 6.16 0.287 1.46 0.476
  T3–4 165 5.80   1.68  
Nodal (N) status N0 95 5.45 0.287 1.54 0.464
  N1 48 6.02   1.65  
  N2 48 6.45   1.87  
Distant metastasis (M) M0 170 5.52 0.023* 1.63 0.532
  M1 21 8.49   1.84  
AJCC stageb I–II 94 5.45 0.144 1.55 0.374
  III–IV 97 6.23   1.74  
Lymphovascular invasion No 141 5.55 0.497 1.70 0.463
  Yes 50 6.67   1.52  
Perineural invasion No 163 5.55 0.549 1.67 0.701
  Yes 28 7.54   1.55  
Extranodal tumor deposits No 163 5.53 0.139 1.66 0.800
  Yes 28 7.66   1.58  
Differentiation G1–G2 149 5.92 0.587 1.64 0.880
  G3–G4 42 5.57   1.68  
Pathology Adenocarcinoma 164 5.93 0.412 1.68 0.465
  Mucinous or signet-ring carcinoma 27 5.30   1.46  
Maximum size (cm)a <5 118 6.02 0.344 1.67 0.687
  >5 73 5.48   1.58  
  1. *A two-tailed p value ≤0.05 was considered statistically significant
  2. aThe mean age and tumor size, respectively
  3. bAbbreviations: AJCC, American Joint Committee on Cancer (AJCC)