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Table 1 Association of PARN, CNOT6, CNOT7 and NOC mRNA levels with clinicopathological characteristics in paired SCC specimens

From: Poly(A)-specific ribonuclease and Nocturnin in squamous cell lung cancer: prognostic value and impact on gene expression

 

Total number of patients

PARN

CNOT6

CNOT7

NOC

Higha (%)

p

High (%)

p

High (%)

p

High (%)

p

Characteristics

         

Age

         

 ≤65

9

8 (88.8)

*

7 (77.8)

 

5 (55.5)

 

5 (55.5)

 

 ≥65

16

7 (43.8)

 

6 (37.5)

 

10 (62.5)

 

12 (75.0)

 

Smoking status

         

 Smokers

21

11 (52.4)

 

12 (57.1)

 

12 (57.1)

 

14 (66.7)

 

 Ex-smokers

4

3 (75.0)

 

1 (25.0)

 

3 (75.0)

 

2 (50.0)

 

Tumor Size

         

 T1-T2

9

5 (55.5)

 

7 (77.8)

 

4 (45.5)

 

5 (55.5)

 

 T3-T4

16

9 (56.3)

 

6 (37.5)

 

10 (62.5)

 

12 (75.0)

 

Lymph Node Metastasis

         

 Negative (N0-N1)

6

3 (50)

 

4 (66.7)

 

3 (50)

 

4 (66.7)

 

 Positive (N2-N3)

19

11 (57.9)

 

9 (47.4)

 

12 (63.1)

 

13 (68.4)

 

Metastasis

         

 Negative (M0)

14

11 (78.6)

 

11 (78.6)

 

10 (71.4)

 

11 (78.6)

 

 Positive (M1)

11

3 (27.3)

 

1 (9.0)

**

5 (45.5)

 

4 (36.4)

 
  1. *p < 0.05; **p < 0.01
  2. aSamples with increased expression levels
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Molecular Cancer

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