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Table 2 Baseline characteristics of CLL patients

From: miR-377-dependent BCL-xL regulation drives chemotherapeutic resistance in B-cell lymphoid malignancies

 

All Patients

BCL-XL < median

 

BCL-XL > median

 

P

(n = 38)

(n = 38)

 

Number

Value (range)

Number

Value (range)

No. (%)

Value (range)

Age, median (range), years

 

64 (38–90)

 

64.5 (38–90)

 

64 (48–87)

N.S.

Sex, male/female

52/24

 

22/16

 

30/8

 

0.08

Rai Stage

N = 76

      

 Early (Stage 0/I/II)

59

 

36

 

23

  

 Advanced (Stage III/IV)

17

 

2

 

15

  

Zap70 positive

18 of 44

 

11 of 24

 

7 of 20

 

0.937

CD38 positive

22 of 53

 

10 of 27

 

12 of 26

 

0.110

FISH

       

 17p

7 of 35

 

1 of 19

 

6 of 16

 

0.275

 11q

6 of 35

 

4 of 19

 

2 of 16

 

0.666

 13q14

22 of 35

 

12 of 18

 

10 of 17

 

0.733

 Trisomy 12

6 of 35

 

2 of 17

 

4 of 16

 

0.398