Fig. 1

TQ reduces NF-κB activity and cell growth, and induces apoptosis in cultured ID8-NGL cells. a Effects of increasing concentrations of TQ on luciferase activity of the NGL reporter (24 h) and on cell growth measured in SRB assays (72 h), expressed as a percentage of control; *p < 0.02 compared to vehicle, Student’s t test. b Levels of apoptosis and proliferation in cells treated with 50 μM TQ (24 h) measured by western blot analysis of cleaved PARP and PCNA expression, respectively. Actin was used as a loading control. c Luciferase activity of the NF-κB reporter measured in ID8-NGL cells cultured in vitro treated with TQ 50 μM for the indicated time periods. Values are mean + SE. *p < 0.01 relative to control; Student’s test