Fig. 1

MiR-634 overexpression induces G1 arrest and causes cell death. a Percentage of A2780 DDP cells in G0/G1, S or G2/M phase 48 or 72 h after transfection with a miR-634 mimic or a scrambled control (n = 3), * = p < 0.05. b A2780 DDP cells were stained with PI and Annexin V 48 or 72 h after transfection with miR-634 mimic or a scrambled control. Depicted are viable (PI/Annexin V negative), early apoptotic (Annexin V positive/PI negative), late (Annexin V positive/PI positive) and dead (PI positive/Annexin V negative) cells (n = 3). c Viability of miR-634 mimic transfected ovarian cancer cells compared to cells transfected with a scrambled mimic (set at 100 %), as determined by an MTT assay 72 h after transfection. Depicted are average values ± SD (n = 3)