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Table 1 Ovarian cancer patient characteristics

From: miR-634 restores drug sensitivity in resistant ovarian cancer cells by targeting the Ras-MAPK pathway

 

Histological subtype

FIGO stage

Grade

Cytotoxic agents used

Response to last Pt containing treatment

Patient 1

Serous

IV

2

Carboplatin, Paclitaxel

PD within 1 month

Patient 2

Serous

IIIc

UK

Carboplatin, Paclitaxel, Gemcitabine

PD within 4 months

Patient 3

Serous

IIIc

3

Carboplatin, Paclitaxel, Gemcitabine

PD within 1 month

Patient 4

Serous

IIIc

2

Carboplatin, Paclitaxel, Olaparib, Caelyx

PD during treatment

Patient 5

Clear cell

IIIc

3

Carboplatin, Ifosfamide

PD within 1 month

Patient 6

Serous

IIIc

3

Carboplatin, Paclitaxel, Caelyx

PD within 5 months

Patient 7

Serous

IIIc

2

 

Chemotherapy naive

  1. UK: Unknown, Pt: Platinum, PD: Progressive disease, Caelyx: liposomal doxorubicin