Fig. 4

Inhibition of miR-362-5p suppressed tumour growth in nude mice. K562 cells infected with lentivirus expressing either miR-362-5p inhibitor (lv-inhibitor) or miR-362-5p inhibitor control (lv-ctrl) were subcutaneously injected into the left axilla of nude mice. a Tumour growth curves were determined by measuring tumor volumes on the indicated days. b & c The graphs are the representative images of the mice (b) and tumours isolated 3 weeks after inoculation. Tumour volumes and weights were calculated. d Expression of GADD45α was analysed by immunohistochemistry in the tissues extracted from nude mice. Data are shown as mean ± SD, **P < 0.05, **P < 0.01