Fig. 6

Comparison of functional network structure in 7df3 and HCT116 cells. a Pattern of functional interaction between a subset of cDNAs in 7df3 TCF-luciferase reporter cells. The thickness of the line represents the relative strength of the synergy. b Pattern of functional interaction in HCT116 cells. Functional interaction between cDNAs is indicated by a line between the relevant nodes when the activity of cDNA pairs exceeded the product of the reporter activity for each cDNA when expressed individually (Student’s t-test, p < 0.01). c Functional interaction between HMGB3/NUCKS1, and IRX3/HDGF in HCT116 cells