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Fig. 1 | Molecular Cancer

Fig. 1

From: BALR-6 regulates cell growth and cell survival in B-lymphoblastic leukemia

Fig. 1

Molecular characterization of BALR-6. a Top: Chromosomal location of BALR-6 in the human genome, surrounding genes, qPCR primers, siRNAs, known annotated exons (green boxes), known introns (black lines) are shown. Bottom: Chip-Seq histone modification map from the Broad institute/ENCODE, taken from UCSC genome browser, shows H3K4m3 and H3K36m3 patterns at LOC339862 in four different cell types indicating active transcription of the lncRNA. b The 100 Vertebrate PhastCons plot from the UCSC whole-genome shows conserved regions among 98 vertebrates including mice and zebrafish throughout the locus. c RACE discovered unannotated exons (magenta) depicted with known annotated exons (green) at LOC339862. d Schematic depicting genomic conservation of the syntenic block among multiple vertebrates, as analyzed by BLAT. Grey box indicates location of homology to BALR-6

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