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Fig. 5 | Molecular Cancer

Fig. 5

From: Subtype-specific accumulation of intracellular zinc pools is associated with the malignant phenotype in breast cancer

Fig. 5

Lack of ZnT2 protein in MDA-MB-231 cells is due to proteasomal degradation. a Representative immunoblot of ZnT2 protein detected in MDA-MB-231 cells treated with MG132 (10 μM; proteasome inhibitor) for 6 h. b Data represent mean Zn transporter: β-actin ± SD, n = 3 samples/cell line. Each experiment was conducted 3 times. Asterisk indicates a significant difference from untreated (−MG132) cells, p < 0.05. c Representative immunoblot of ZnT2 protein detected in MDA-MB-231 cells treated with chloriquine (CQ, 30 μM; lysosome inhibitor) for 24 h. d Data represent mean Zn transporter: β-actin ± SD, n = 3 samples/cell line. Each experiment was conducted 3 times

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Molecular Cancer

ISSN: 1476-4598