Fig. 6
From: Effect of low doses of actinomycin D on neuroblastoma cell lines
Effect of the combination of Actinomycin D with SAHA in vivo. a Tumor size observed in mice after 14 days of each treatment. b Tumor volume increase over time, expressed as fold increase over the initial tumor volume. Error bars show ± SEM of at least 10 tumor replicates on eight different mice for each treatment. c Final volume of each of the tumors analyzed. d RNA levels of 45S rRNA was measured after 14 days of each treatment. Values represent the average ± SEM of three different tumors for each treatment. e Hematoxylin and eosin (H&E), Ki67 and p53 stainings were obtained after 14 days of indicated treatment. f Graphic representation of the p53 staining values