Fig. 2From: Does VEGF facilitate local tumor growth and spread into the abdominal cavity by suppressing endothelial cell adhesion, thus increasing vascular peritoneal permeability followed by ascites production in ovarian cancer?VEGF levels in serum in relation to tumor stage and resection status after surgery. Comparison of VEGF levels (pg/ml) between different groups of tumor sizes (T1-2 vs. T3-4) on the different days of measurement (day 0, day 2 and day 4) showed numerically but not significantly higher values in the group of T3-tumors compared to T1-ovarian cancers (all p > 0.07). The differences between the different days of measurement (decrease at day 2 and increase at day 4) were significant in the T3-group (p < 0.003) (a). Analysis of VEGF levels in the ovarian cancer patient group with no residual tumor after surgery (TR 0) and remaining tumor (TR > 1 cm or TR < 1 cm). We revealed significant higher values in the group with residual tumor (both < and > 1 cm) in comparison to the group with no remaining tumor measured before operation at day 0 (p = 0.049 and p = 0.003). Significant (all p < 0.02) differences between the various days of measurement (0, 2 and 4 days) were detected in all three groups (TR 0, TR < 1 cm, TR > 1 cm), with a decrease in serum VEGF levels at day 2 and an increase on day 4 (b)Back to article page