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Fig. 2 | Molecular Cancer

Fig. 2

From: Does VEGF facilitate local tumor growth and spread into the abdominal cavity by suppressing endothelial cell adhesion, thus increasing vascular peritoneal permeability followed by ascites production in ovarian cancer?

Fig. 2

VEGF levels in serum in relation to tumor stage and resection status after surgery. Comparison of VEGF levels (pg/ml) between different groups of tumor sizes (T1-2 vs. T3-4) on the different days of measurement (day 0, day 2 and day 4) showed numerically but not significantly higher values in the group of T3-tumors compared to T1-ovarian cancers (all p > 0.07). The differences between the different days of measurement (decrease at day 2 and increase at day 4) were significant in the T3-group (p < 0.003) (a). Analysis of VEGF levels in the ovarian cancer patient group with no residual tumor after surgery (TR 0) and remaining tumor (TR > 1 cm or TR < 1 cm). We revealed significant higher values in the group with residual tumor (both < and > 1 cm) in comparison to the group with no remaining tumor measured before operation at day 0 (p = 0.049 and p = 0.003). Significant (all p < 0.02) differences between the various days of measurement (0, 2 and 4 days) were detected in all three groups (TR 0, TR < 1 cm, TR > 1 cm), with a decrease in serum VEGF levels at day 2 and an increase on day 4 (b)

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