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Table 3 Cox regression analysis of patients with HCC

From: Over-expression of cathepsin B in hepatocellular carcinomas predicts poor prognosis of HCC patients

Variables Univariate P value
HR CI (95 %)
CTSB expression (1 = down,2 = over) 5.132 3.125 ~ 6.037 0.000
Gender (1 = male,2 = female) 0.511 0.327 ~ 1.078 0.106
Age (1 < 50,2 ≥ 50) 0.468 0.279 ~ 0.998 0.412
Serum HBsAg (1 = negative,2 = positive) 1.033 0.723 ~ 2.411 0.107
Serum AFP (1 < 25 ng/ml,2 ≥ 25 ng/ml) 3.415 2.379 ~ 4.866 0.009
Tumor size (1 < 5 cm,2 ≥ 5 cm) 1.756 1.218 ~ 3.321 0.039
Cirrhosis (1 = Absence,2 = Presence) 0.932 0.782 ~ 1.687 0.443
Metastasis/Recurrence (1 = no,2 = yes) 5.002 3.437 ~ 7.312 0.000
UICC stage (1 = I + II,2 = III + IV) 1.958 1.021 ~ 4.190 0.042
Edmondson grade (1 = High (III/IV),2 = Low (I/II)) 1.412 0.783 ~ 2.224 0.098