Fig. 8From: ERK mediated upregulation of death receptor 5 overcomes the lack of p53 functionality in the diaminothiazole DAT1 induced apoptosis in colon cancer models: efficiency of DAT1 in Ras-Raf mutated cellsSignaling pathway elucidated by DAT1 in tumour tissues. a-b. Sections were made from control and DAT1 treated tumour tissues and immunohistochemistry was performed using the respective antibodies as described in Fig. 7. c The positively stained area were quantified using Image J and were plotted to show activation of the respective proteins followed by determination of statistical significance using unpaired t testBack to article page