Table 2 Comparison of IC₅₀ values of DAT1 in Ras/Raf mutated and wild type cell lines. The respective cell lines were treated with DAT1 for 48 h at different concentrations followed by MTT assay. IC₅₀ values were calculated using the programme Origin

From: ERK mediated upregulation of death receptor 5 overcomes the lack of p53 functionality in the diaminothiazole DAT1 induced apoptosis in colon cancer models: efficiency of DAT1 in Ras-Raf mutated cells