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Fig. 7 | Molecular Cancer

Fig. 7

From: Oral squamous cell carcinoma: microRNA expression profiling and integrative analyses for elucidation of tumourigenesis mechanism

Fig. 7

MicroRNAs downregulated in OSCC target multiple genes in the PI3K/AKT pathway. Shown here are the 5 miRNAs significantly downregulated in OSCC and their validated target genes that participate in the PI3K/Akt signaling pathway (hsa04151). Blue rectangles represent the miRNAs, yellow rectangles represent genes targeted by only one miRNA, and orange rectangles represent genes targeted by more than one miRNA. Green rectangles represent genes that are not targeted by any of the miRNAs studied herein. Figure developed from the output of Diana miRpath V.2

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