Table 3 Circulating microRNAs in human leukemia
From: Clinical significance of microRNAs in chronic and acute human leukemia
Circulating miRNA | Expression in patients | Association with blood cell count | Predict prognosis | Predict Disease progression | Predict Drug response |
|---|---|---|---|---|---|
miR-29 | up in CLL exosome | Yes | Yes | – | – |
miR-150 | up in CLL exosome, low in AML plasma | Yes | Yes | – | Yes |
miR-155 | up in CLL exosome, up in AML plasma | Yes | Yes | Yes | Yes |
miR-181b-5p | up in AML plasma | – | Yes | – | Yes |
miR-210 | up in AML serum | – | Yes | – | Yes |
miR-375 | up in AML serum | – | Yes | – | – |
miR-511 | up in B-ALL plasma | – | – | – | – |
miR-222 | up in B-ALL plasma | – | – | – | – |
miR-34a | up in B-ALL plasma | – | – | – | – |
miR-199a-3p | low in B-ALL plasma | – | – | – | – |
miR-223 | low in B-ALL plasma | – | – | – | – |
miR-221 | low in B-ALL plasma | – | – | – | – |
miR-26a | low in B-ALL plasma | – | – | – | – |
let-7d | low in AML plasma | – | – | – | – |
miR-339 | low in AML plasma | – | – | – | – |
miR-342 | low in AML plasma | – | Yes | – | – |
let-7b | up in AML plasma | – | – | – | – |
miR-523 | up in AML plasma | – | – | – | – |
miR-328 | low in AML plasma | Yes | Yes | – | – |