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Fig. 2 | Molecular Cancer

Fig. 2

From: Metallothionein-1 as a biomarker of altered redox metabolism in hepatocellular carcinoma cells exposed to sorafenib

Fig. 2

Pharmacological antioxidants prevent the induction of MT1G induced by sorafenib. a: MT1G mRNA induction in Huh7 cells treated with sorafenib 10 μM and DFX 100 μM (preincubated 1 h) for 18 h. b Induction of MT1G mRNA in Huh7 cells exposed for 18 h to sorafenib 10 μM and/or NAC 10 mM (preincubated 1 h). *: p < 0.05 compared to sorafenib alone. c Induction of MT1G mRNA in Huh7 cells exposed to 300 μM sulfasalazine and/or NAC 10 mM (preincubated 1 h) for 18 h. *: p < 0.05 compared to sulfasalazine alone

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Molecular Cancer

ISSN: 1476-4598