Fig. 6

MTT assay analysis of cell survival in LS-174 T and RKO cells post treatment of cisplatin. We analysed cell survival fractions for the cells that are expressing the fusion gene (LS-174 T) as compared with non-expressing cells (RKO) post treatment of cisplatin (5 μg/ml). MTT assay was used for the cell viability analysis and an averaged absorbance was recorded 24, 48 and 72 h post treatment. Cell viability analysis showed that the LS-174 T cells had 60 and 27.5 % of viable cells compared to non-treatment controls 48 h and 72 h post treatment with cisplatin. In contrast, there were 80 and 46 % of viable cells in the RKO population 48 h and 72 h post cisplatin treatment. The LS-174 T cell was more sensitive to the treatment of cisplatin